Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Spinal cord compression

External mechanical compression of the spinal cord.


Total: 3

                      


(per page)
PMID (PMCID)
28775247
(5551928)
MALE Middle Aged
Spinal Abscess Caused by Salmonella Bacteremia in a Patient with Primary Myelofibrosis.
Fareed S, Nashwan AJ, Abu Jarir S, Husain A, Suliman DS, Ibrahim F, Moustafa A, Akhter MS, Yassin MA.
Am J Case Rep. 2017;18:859-864.
BACKGROUND In Primary Myelofibrosis (PMF; a clonal disorder arising from the neoplastic transformation of early hematopoietic stem cells) patients, spinal cord compression (SCC) is a common complication or even a presentation symptom due to extramedullary hematopoiesis (EMH).
28775247
(5551928)
MALE Middle Aged
Spinal Abscess Caused by Salmonella Bacteremia in a Patient with Primary Myelofibrosis.
Fareed S, Nashwan AJ, Abu Jarir S, Husain A, Suliman DS, Ibrahim F, Moustafa A, Akhter MS, Yassin MA.
Am J Case Rep. 2017;18:859-864.
CASE REPORT We are reporting the case of a 50-year-old male with primary myelofibrosis and long-standing splenomegaly with back pain as a presenting symptom who was found to have spinal cord compression.
9351112
MALE Adult
Imaging of spinal cord compression due to thoracic extramedullary haematopoiesis in myelofibrosis.
Guermazi A, Miaux Y, Chiras J.
Neuroradiology. 1997;39(10):733-6.
We describe a case of spinal cord compression secondary to extramedullary haematopoiesis in a patient with primary myelofibrosis.