Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Pleural effusion

The presence of an excessive amount of fluid in the pleural cavity.

Total: 7

(per page)

PMID (PMCID)
23618686	FEMALE	Adult
	A case report on a patient who presented with myelofibrosis, developed breast cancer with myeloid metaplasia, and finally showed immature NK-cell leukemia or AML without maturation with CD56 expression transformation in the pleura with extramedullary hematopoiesis: a 25-year course.
	Oka K, Nagayama R, Yonekawa N, Koyamatsu S, Mori N. Pathol Res Pract. 2013;209(5):319-22.
	This study reports a female patient who suffered from primary myelofibrosis at 38 years of age, breast cancer with myeloid metaplasia at 49 years of age, and pleural effusion and multiple subcutaneous nodules at 62 years of age.
16862981	MALE	Middle Aged
	[Low dose whole lung irradiation for intractable pleural effusion due to idiopathic myelofibrosis].
	Wakita S, Yamaguchi H, Okabe M, Takeuchi J, Tamai H, Nakamura K, Tajika K, Inokuchi K, Dan K. Rinsho Ketsueki. 2006;47(6):526-30.
	A 63-year-old man with idiopathic myelofibrosis, diagnosed on Sept. 2004 and treated with hydroxyurea (HU), was admitted to our hospital on March 2005 because of dyspnea and pleural effusion on the right side.
16862981	MALE	Middle Aged
	[Low dose whole lung irradiation for intractable pleural effusion due to idiopathic myelofibrosis].
	Wakita S, Yamaguchi H, Okabe M, Takeuchi J, Tamai H, Nakamura K, Tajika K, Inokuchi K, Dan K. Rinsho Ketsueki. 2006;47(6):526-30.
	[Low dose whole lung irradiation for intractable pleural effusion due to idiopathic myelofibrosis].
15160962	MALE
	Agnogenic myeloid metaplasia with pleural extramedullary leukemic transformation.
	Nadrous HF, Krowka MJ, McClure RF, Tefferi A, Lim KG. Leuk Lymphoma. 2004;45(4):815-8.
	Herein we describe a 71-year-old man with newly diagnosed agnogenic myeloid metaplasia who was evaluated for progressively worsening dyspnea, pulmonary hypertension and bilateral pleural effusions.
11999361	FEMALE	Middle Aged
	A pleural effusion caused by fibrous hematopoietic tumor successfully treated with prednisolone in a patient with agnogenic myeloid metaplasia with myelofibrosis.
	Hirayama Y, Koyama R, Nagai T, Matsunaga T, Kogawa lK, Sakamaki S, Kokai Y, Niitsu Y. Int J Hematol. 2002;75(3):305-8.
	A pleural effusion caused by fibrous hematopoietic tumor successfully treated with prednisolone in a patient with agnogenic myeloid metaplasia with myelofibrosis.
9460572	MALE	Middle Aged
	Pleural effusion secondary to extramedullary haemopoiesis in a patient with idiopathic myelofibrosis responding to pleurodesis and hydroxyurea.
	Jowitt SN, Burke DK, Leggat HM, Lewis PS, Cryer RJ. Clin Lab Haematol. 1997;19(4):283-5.
	A case of idiopathic myelofibrosis presenting with a pleural effusion secondary to extramedullary haemopoeisis is described.
1419799	MALE	Middle Aged
	Establishment of a novel granulocytic sarcoma cell line which can adhere to dermal fibroblasts from a patient with granulocytic sarcoma in dermal tissues and myelofibrosis.
	Kobayashi M, Imamura M, Soga R, Tsuda Y, Maeda S, Iwasaki H, Sugiura M, Ohizumi H, Musashi M, Morioka M, et al.. Br J Haematol. 1992;82(1):26-31.
	A novel human myeloid cell line, designated HSM-1, has been established from the pleural effusion of a patient with granulocytic sarcoma (GS) who had been followed as having primary myelofibrosis for 10 years.