Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Pulmonary fibrosis

Replacement of normal lung tissues by fibroblasts and collagen.

Total: 2

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PMID (PMCID)
11279314	MALE	Middle Aged
	Bilateral interstitial pneumonic shadows caused by perivascular fibrosis and extramedullary megakaryopoiesis of the lung in a case of advanced agnogenic myeloid metaplasia and myelofibrosis.
	Ueno H, Yoneda R, Ogawa W, Yoon S, Kitazawa S, Kitazawa R, Kasuga M. Acta Haematol. 2000;104(4):212-6.
	This is the first description of an association between pulmonary fibrosis and PDGF in idiopathic myelofibrosis.
8575594	MALE
	Pulmonary fibrosis and sea-blue histiocyte infiltration in a patient with primary myelofibrosis.
	Yamauchi K, Shimamura K. Eur Respir J. 1995;8(9):1620-3.
	Pulmonary fibrosis and sea-blue histiocyte infiltration in a patient with primary myelofibrosis.