Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Gastrointestinal hemorrhage

Hemorrhage affecting the gastrointestinal tract.


Total: 1

                      


(per page)
PMID (PMCID)
20181038
(2830976)
OTHER
Acute variceal bleeding in a patient with idiopathic myelofibrosis successfully treated with endoscopic variceal band ligation and chemotherapy: a case report.
Tamaki K, Otaka M, Sakamoto N, Matsumoto K, Yamashina S, Watanabe S.
J Med Case Rep. 2010;4:25.
Gastrointestinal hemorrhages, which are due mostly to the rupture of the esophageal varices, have been sporadically reported to be an infrequent complication of idiopathic myelofibrosis.