Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Lymphadenopathy

Enlargment (swelling) of a lymph node.

Total: 3

(per page)

PMID (PMCID)
20235031	FEMALE	Middle Aged
	[Lymphadenopathy and diabetes insipidus - association].
	Zahnd R, Oestmann A, Ebnother M. Praxis (Bern 1994). 2010;99(6):381-4.
	We report the case of a 62 year old women with chronic idiopathic myelofibrosis who developed acute lymphadenopathy.
4015283	MALE	Adult
	Extramedullary hematopoiesis. A cause of severe generalized lymphadenopathy in agnogenic myeloid metaplasia.
	Williams ME, Innes DJ, Hutchison WT, Hess CE. Arch Intern Med. 1985;145(7):1308-9.
	Although microscopic evidence of extramedullary hematopoiesis in lymph nodes is a frequent finding in autopsy studies of patients with agnogenic myeloid metaplasia, clinically significant lymphadenopathy is a rare occurrence.
953969	FEMALE	Middle Aged
	Blastic phase of agnogenic myeloid metaplasia simulating malignant lymphoma.
	Cehreli C, Ezdinli EZ, Li CY, Krmpotic E. Cancer. 1976;38(3):1297-305.
	The literature is reviewed regarding the incidence of prominent lymphadenopathy and chromosome abnormalities in agnogenic myeloid metaplasia and other myeloproliferative disorders.