Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Back pain

An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the back.


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PMID (PMCID)
28775247
(5551928)
MALE Middle Aged
Spinal Abscess Caused by Salmonella Bacteremia in a Patient with Primary Myelofibrosis.
Fareed S, Nashwan AJ, Abu Jarir S, Husain A, Suliman DS, Ibrahim F, Moustafa A, Akhter MS, Yassin MA.
Am J Case Rep. 2017;18:859-864.
CASE REPORT We are reporting the case of a 50-year-old male with primary myelofibrosis and long-standing splenomegaly with back pain as a presenting symptom who was found to have spinal cord compression.