Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Hypoxemia

An abnormally low level of blood oxygen.


Total: 1

                      


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PMID (PMCID)
16321815
MALE
Agnogenic myeloid metaplasia with pulmonary hematopoiesis.
Boula A, Mantadakis E, Xilouri I, Foudoulakis A, Samonis G.
Hematology. 2005;10(6):501-3.
We report the case of a 77-year-old man with agnogenic myeloid metaplasia (AMM) treated with hydroxyurea, who seven years after diagnosis presented with dyspnea and severe hypoxemia.