Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Carcinoma

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus).


Total: 3

                      


(per page)
PMID (PMCID)
7490324
MALE Middle Aged
Osteolytic bone lesions in a patient with idiopathic myelofibrosis and bronchial carcinoma.
Clutterbuck DJ, Morrison AE, Ludlam CA.
J Clin Pathol. 1995;48(9):867-8.
Osteolytic bone lesions in a patient with idiopathic myelofibrosis and bronchial carcinoma.
3982370
FEMALE Adult
Secondary myelofibrosis with metastatic breast cancer simulating agnogenic myeloid metaplasia: report of a case and review of the literature.
Yablonski-Peretz T, Sulkes A, Polliack A, Weshler Z, Okon E, Catane R.
Med Pediatr Oncol. 1985;13(2):92-6.
These findings are rare and myeloid metaplasia with striking extramedullary hematopoiesis causing massive splenomegaly and mimicking agnogenic myeloid metaplasia is seldom seen in patients with metastatic carcinoma.
3982370
FEMALE Adult
Secondary myelofibrosis with metastatic breast cancer simulating agnogenic myeloid metaplasia: report of a case and review of the literature.
Yablonski-Peretz T, Sulkes A, Polliack A, Weshler Z, Okon E, Catane R.
Med Pediatr Oncol. 1985;13(2):92-6.
A patient with carcinoma of the breast, who developed a clinical syndrome resembling agnogenic myeloid metaplasia, is described.