Alpha-thalassemia

An inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture depending on the number of affected alleles.

Microcytic anemia

A kind of anemia in which the volume of the red blood cells is reduced.


Total: 3

                       


(per page)
PMID (PMCID)
25863109
 MALE
Hemoglobin Constant Spring exhibits prolonged ex vivo stability when assessed by HPLC.
Estey MP, Belletrutti M, Rodriguez-Capote K, Higgins T.
Clin Biochem. 2015;48(10-11):709-12.
1) To investigate the presence of hemoglobin Constant Spring (HbCS) in a patientwith severe microcytic anemia who had previously been diagnosed with alpha thalassemia minor.
17412572
 MIXED_SAMPLE Infant
[Failure to thrive and psychomotor regression revealing vitamin B12 deficiency in 3 infants].
Mathey C, Di Marco JN, Poujol A, Cournelle MA, Brevaut V, Livet MO, Chabrol B, Michel G.
Arch Pediatr. 2007;14(5):467-71.
Blood cell count showed a macrocytosis without anemia (case 2-3) and a severe microcytic anemia for the first case caused by a mild alpha-thalassemia, with megaloblastic bone marrow.
17006749
 MALE Adult
A case of alpha-thalassemia-2 associated with pulmonary infarction.
Hayashi S, Matsuoka H, Harano T, Harano K, Nakahara H, Tachibana I, Kida H, Kawasaki T, Kyotani S, Oka Y, Sakatani M, Kawase I.
Lung. 2006;184(4):223-7.
We have evaluated a 21-year-old male alpha-thalassemia-2 patient who had profound microcytic anemia and pulmonary infarction.