Beta-thalassemia

Beta-thalassemia (BT) is characterized by deficiency (Beta+) or absence (Beta0) of synthesis of the beta globin chains of hemoglobin (Hb).

Congestive heart failure

The presence of an abnormality of cardiac function that is responsible for the failure of the heart to pump blood at a rate that is commensurate with the needs of the tissues or a state in which abnormally elevated filling pressures are required for the heart to do so. Heart failure is frequently related to a defect in myocardial contraction.


Total: 2

                       


(per page)
PMID (PMCID)
10951965
 MALE Adult
[Pulmonary hypertension in patient with beta-thalassemia major].
Merault JM, Escamilla R, Degano B, Guittard J, Hermant C, Krempf M.
Rev Mal Respir. 2000;17(3):689-91.
In beta-thalassemia, whereas congestive heart failure is common and due to cardiac hemosiderin deposition, PH appears to be non rare but its etiopathogenic mechanism remain unclear and probably non univoqual.
3959597
 MALE Adult
Decreased bone magnesium in beta thalassemia with spinal osteoporosis.
Cohen L, Bitterman H, Froom P, Aghai E.
Magnesium. 1986;5(1):43-6.
In the absence of endocrine abnormalities and congestive heart failure, this low bone Mg suggests Mg depletion in uncomplicated beta thalassemia.