Beta-thalassemia

Beta-thalassemia (BT) is characterized by deficiency (Beta+) or absence (Beta0) of synthesis of the beta globin chains of hemoglobin (Hb).

Hypersplenism

A malfunctioning of the spleen in which it prematurely destroys red blood cells.


Total: 3

                      


(per page)
PMID (PMCID)
15682853
FEMALE Middle Aged
Diffuse splenic Tc-99m MDP uptake in hypersplenic patient.
Yapar AF, Aydin M, Reyhan M.
Ann Nucl Med. 2004;18(8):703-5.
Her hemoglobin analysis and hematologic findings were interpreted as being consistent with sickle cell beta+ thalassemia and also hypersplenism.
10482027
FEMALE Adult
Campylobacter bacteremia and pneumonia in two splenectomized patients.
Sakran W, Raz R, Levi Y, Colodner R, Koren A.
Eur J Clin Microbiol Infect Dis. 1999;18(7):496-8.
Two patients with beta thalassemia who had undergone splenectomy for hypersplenism were admitted to the hospital with high fever and lobar pneumonia.
2649825
FEMALE Adult
Successful full-term pregnancy in homozygous beta-thalassemia major: case report and review of the literature.
Mordel N, Birkenfeld A, Goldfarb AN, Rachmilewitz EA.
Obstet Gynecol. 1989;73(5 Pt 2):837-40.
Patients afflicted by homozygous beta-thalassemia suffer from severe anemia and hypersplenism and are dependent on blood transfusions.