IMAGe syndrome is characterized by the association of <i>I</i>ntrauterine growth retardation, <i>M</i>etaphyseal dysplasia (and short limbs), <i>A</i>drenal hypoplasia congenita, and <i>Ge</i>nital anomalies. It has been described in less than 20 cases. The patients also present with dysmorphic features (frontal bossing, broad nasal bridge, low-set ears). In boys, genital anomalies include bilateral cryptorchidism, hypospadias, micropenis, and hypogonadotropic hypogonadism. This syndrome is likely to be transmitted as an autosomal recessive trait.
