AL amyloidosis

A plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ.

Jaundice

Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.


Total: 4

                      


(per page)
PMID (PMCID)
22750921
FEMALE
Primary amyloidosis presenting as cholestatic jaundice.
Polanski LT, Markar SR, Satyadas T, Praseedom R, Shaw A.
BMJ Case Rep. 2010;2010:.
Primary amyloidosis presenting as cholestatic jaundice.
17354133
MALE Middle Aged
Magnetic resonance imaging with liver-specific contrast agent in primary amyloidosis and intrahepatic cholestasis.
Moller JM, Santoni-Rugiu E, Chabanova E, Logager V, Hansen AB, Thomsen HS.
Acta Radiol. 2007;48(2):145-9.
Here, we report on a patient with renal failure caused by primary amyloidosis (AL type) who developed jaundice.
10078828
MIXED_SAMPLE Middle Aged
Cholestatic jaundice in two patients with primary amyloidosis: ultrastructural findings of the liver.
Iwai M, Ishii Y, Mori T, Harada Y, Kitagawa Y, Kashiwadani M, Ou O, Okanoue T, Kashima K.
J Clin Gastroenterol. 1999;28(2):162-6.
Two patients with primary amyloidosis (amyloid light chain case) and severe cholestatic jaundice are described.
7959246
MIXED_SAMPLE Middle Aged
Primary amyloidosis and severe intrahepatic cholestatic jaundice.
Peters RA, Koukoulis G, Gimson A, Portmann B, Westaby D, Williams R.
Gut. 1994;35(9):1322-5.
Primary amyloidosis and severe intrahepatic cholestatic jaundice.