AL amyloidosis

A plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ.

Muscle weakness

Reduced strength of muscles.


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PMID (PMCID)
28367947
 MALE
A case of amyloid myopathy diagnosed during the treatment of myopathy associated with anti-signal recognition particle antibodies.
Kawakami N, Katsuyama Y, Hagiwara Y, Yoshida H, Kim K, Harada K.
Rinsho Shinkeigaku. 2017;57(4):168-173.
The patient was diagnosed with amyloid myopathy, and therapy for systemic amyloid light chain amyloidosis caused muscle weakness to diminish.