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AL amyloidosis

A plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ.

Pericardial effusion

Accumulation of fluid within the pericardium.

Total: 1

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PMID (PMCID)
11279315	MALE	Adult
	Colchicine: an effective treatment for refractory malignant pericardial effusion.
	Ng T, Gatt A, Pagliuca A, Mufti GJ. Acta Haematol. 2000;104(4):217-9.
	We report a patient with AL amyloidosis and chemo-resistant light-chain multiple myeloma who developed a progressive malignant pericardial effusion leading to cardiac tamponade.