AL amyloidosis

A plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ.

Respiratory arrest



Total: 1

                      


(per page)
PMID (PMCID)
10871736
FEMALE Middle Aged
Severe respiratory depression after dimethylsulphoxide-containing autologous stem cell infusion in a patient with AL amyloidosis.
Benekli M, Anderson B, Wentling D, Bernstein S, Czuczman M, McCarthy P.
Bone Marrow Transplant. 2000;25(12):1299-301.
We report here a 58-year-old female with AL amyloidosis who developed an unexpected episode of respiratory arrest a few seconds after the beginning of thawed stem cell product infusion.