AL amyloidosis

A plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ.

Ecchymosis

A purpuric lesion that is larger than 1 cm in diameter.


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PMID (PMCID)
18203516
 MALE
[Primary amyloidosis associated with IgD-lambda M-proteinemia].
Kimura S, Iwatsuka R, Aoki T, Odawara J, Asada N, Yamakura M, Takeuchi M, Matsue K.
Rinsho Ketsueki. 2007;48(12):1555-8.
Because the patient had macroglossia and multiple ecchymosis in the face and neck, primary amyloidosis was suspected.