AA amyloidosis

Secondary amyloidosis is a form of amyloidosis (see this term), that complicates chronic inflammatory disorders (mainly rheumatoid arthritis, see this term) and is characterized by the aggregation and deposition of amyloid fibrils composed of serum amyloid A protein, an acute phase reactant. Although spleen, suprarenal gland, liver and gut are frequent sites of amyloid deposition, the clinical picture is dominated by renal involvement.

Chronic infection

Presence of a protracted or persistent infection by a pathogen potentially related to an underlying abnormality of the immune system that is not able to clear the infection.

Total: 6

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PMID (PMCID)
25340157 (4206034)	OTHER
	Amyloid A amyloidosis with subcutaneous drug abuse.
	Mendoza JM, Peev V, Ponce MA, Thomas DB, Nayer A. J Renal Inj Prev. 2014;3(1):11-6.
	Amyloid A (AA) amyloidosis is a systemic form of amyloidosis secondary to chronic infections and inflammatory disorders.
25174445	MALE
	De novo amyloidosis in a renal transplant patient.
	Ylmaz S, Ozcakar ZB, Bulum B, Kiremitci S, Ensari A, Ekim M, Keven K, Yalcnkaya F. Pediatr Transplant. 2014;18(8):E259-61.
	Systemic AA amyloidosis is a serious complication of many chronic inflammatory disorders and chronic infections.
21519822	MALE	Adult
	A rare case of reversible acquired AA-type renal amyloidosis in a chronic filariasis patient receiving antifilarial therapy.
	Nayak HK, Daga MK, Garg Sk, Sinha Nk, Kumar R, Mohanty PK, Pandey BK. Clin Exp Nephrol. 2011;15(4):591-5.
	Although various chronic infections can lead to secondary renal amyloidosis, this is the first case reported in world literature where secondary amyloidosis developed as a complication of chronic filarial infection due to W. bancrofti.
17701473	MALE	Adult
	Secondary amyloidosis in a needle phobic intra-venous drug user.
	Miranda BH, Connolly JO, Burns AP. Amyloid. 2007;14(3):255-8.
	Recent epidemiological data is discussed that suggests geographical location and the subcutaneous (SC) route of drug administration are both contributing factors to the development of AA amyloidosis and not chronic infection with HIV, HBV or HCV.
17170630	MALE	Adult
	Acute renal failure and nephrotic range proteinuria due to amyloidosis in an HIV-infected patient.
	Chan-Tack KM, Ahuja N, Weinman EJ, Wali RK, Uche A, Greisman LA, Drachenberg C, Hawkins PN, Redfield RR. Am J Med Sci. 2006;332(6):364-7.
	AA amyloidosis occurs as a complication of chronic infection or chronic inflammatory disease.
18652280	MALE	Middle Aged
	[Secondary amyloidosis connected with neoplasma of urinary bladder and acquired disorders of blood coagulation. Case report].
	Bednarek-Skublewska A, Majdan M, Targonska-Stepniak B, Ksiazek A. Pol Arch Med Wewn. 2006;116(3):868-72.
	The secondary amyloidosis is associated with systemic inflammatory processes, chronic infections or neoplasm.