Chronic neutrophilic leukemia


Hepatosplenomegaly

Simultaneous enlargement of the liver and spleen.


Total: 5

                       


(per page)
PMID (PMCID)
30473959
(6248686)
 OTHER
Colony-stimulating Factor 3 Receptor Mutated Chronic Neutrophilic Leukemia: A Rare Case Report.
Thapa B, Jamhour C, Chahine J, Rogers HJ, Daw H.
Cureus. 2018;10(9):e3326.
Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative neoplasm, which is characterized by sustained peripheral leukocytosis with neutrophilia, hepatosplenomegaly, and hypercellularity of the bone marrow, with less than 5% myeloblasts along with normal neutrophil maturationand no dysplasia.
23761837
(3678609)
 OTHER
Deletion of chromosome 17 as a novel cytogenetic finding in chronic neutrophilic leukemia: A case report.
Chen Y, Wang S, Wang W.
Oncol Lett. 2013;5(5):1704-1706.
Chronic neutrophilic leukemia (CNL) is an infrequently encountered myeloproliferative disorder characterized by sustained neutrophilic leukocytosis, hepatosplenomegaly and the absence of the Philadelphia chromosome.
15683121
(4531574)
 FEMALE
A case of transition of polycythemia vera to chronic neutrophilic leukemia.
Lee SS, Moon JH, Ha JW, Lee YK, Ahn JS, Zang DY, Kim HJ.
Korean J Intern Med. 2004;19(4):285-8.
Chronic Neutrophilic Leukemia (CNL) is a rare myeloproliferative disorder characterized by a persistent increase of mature peripheral neutrophils, myeloid hyperplasia in bone marrow, hepatosplenomegaly, elevated neutrophil alkaline phosphatase (NAP) and absence of Philadelphia chromosome, with no evidence of infection or malignancy sufficient to mimic a leukemoid reaction.
12035370
 MALE
Chronic neutrophilic leukemia--a case report.
Umashankar T, Venugopal N, Patil P.
Indian J Pathol Microbiol. 2001;44(4):471-2.
Chronic neutrophilic leukemia is a rare hematological disorder with hepatosplenomegaly and sustained mature neutrophilic leucocytosis.
3469004
 FEMALE
Neutrophilic leukemia accompanied by hemorrhagic diathesis: report of two cases.
Hossfeld DK, Lokhorst HW, Garbrecht M.
Blut. 1987;54(2):109-13.
Chronic neutrophilic leukemia, which may be regarded a variant of myeloproliferative disease, is associated with mature peripheral neutrophilia, hepatosplenomegaly, tissue infiltration by mature and immature granulocytes, an elevated leucocyte alkaline phosphatase score, absence of the Ph1 chromosome and elevated vitamin B12.