Plasmacytoma

Plasmacytoma is a localized mass of neoplastic monoclonal plasma cells that represents approximately 5% of all plasma cell neoplasms. There are two separate entities: primary plasmacytoma of the bone and extramedullary plasmacytoma of the soft tissues. Of the extramedullary plasmacytomas, 80% occur in the head and neck, usually in the upper respiratory tract. The median age at diagnosis is 50 years and the male to female ratio is 3:1. Long-term survival is possible following local radiotherapy, particularly for soft tissue presentations.

Diplopia

Diplopia is a condition in which a single object is perceived as two images, it is also known as double vision.


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(per page)
PMID (PMCID)
24164055
 FEMALE Middle Aged
Diplopia and variable ptosis as the sole initial findings in a case of orbital plasmacytoma and multiple myeloma.
Galea M, McMillan N, Weir C.
Semin Ophthalmol. 2015;30(3):235-7.
Diplopia and variable ptosis as the sole initial findings in a case of orbital plasmacytoma and multiple myeloma.
24164055
 FEMALE Middle Aged
Diplopia and variable ptosis as the sole initial findings in a case of orbital plasmacytoma and multiple myeloma.
Galea M, McMillan N, Weir C.
Semin Ophthalmol. 2015;30(3):235-7.
We present an unusual case of orbital plasmacytoma and advanced multiple myeloma where the sole presenting symptoms were those of diplopia and ptosis.
24171339
 MALE Young Adult
Ophthalmic manifestations of haematological disorders.
Charles KS, Leelah N, Boodoo L, Murray DC.
West Indian Med J. 2013;62(1):99-103.
Waldenstrom's macroglobulinaemia caused bilateral central retinal vein occlusion, proptosis was the presenting feature of retro-orbital plasmacytoma in relapsed multiple myeloma, a red painful eye was due to neovascular glaucoma in primary polycythaemia, bilateral VIth nerve palsy caused convergent squint and diplopia in meningeal relapse of acute lymphoblastic leukaemia and lymphoma of the eyelid caused complete ptosis.