Plasmacytoma

Plasmacytoma is a localized mass of neoplastic monoclonal plasma cells that represents approximately 5% of all plasma cell neoplasms. There are two separate entities: primary plasmacytoma of the bone and extramedullary plasmacytoma of the soft tissues. Of the extramedullary plasmacytomas, 80% occur in the head and neck, usually in the upper respiratory tract. The median age at diagnosis is 50 years and the male to female ratio is 3:1. Long-term survival is possible following local radiotherapy, particularly for soft tissue presentations.

Hepatosplenomegaly

Simultaneous enlargement of the liver and spleen.

Total: 2

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PMID (PMCID)
2276681	MALE	Middle Aged
	POEMS syndrome: a case report.
	Bisail M, Cossu A, Massarelli G, Tanda F, Agnetti V, Traccis S, Cassisa L, Puliga MV, Bartoli E. Haematologica. 1990;75(4):384-6.
	A case of POEMS syndrome in a 43-year-old male with polyneuropathy, osteolytic lesion of the basin due to solitary IgA-lambda plasmacytoma, cutaneous scleroderma-like changes, diffuse lymphadenopathy and hepatosplenomegaly is described.
7413545	FEMALE	Middle Aged
	Plasma cell dyscrasia with polyneuritis and dermato-endocrine alterations. Report of a new case outside Japan.
	Moya-Mir MS, Martin-Martin F, Barbadillo R, Cuervas-Mons V, Martin-Jimenez T, Sanchez-Miro I, Garcia-Merino JA. Postgrad Med J. 1980;56(656):427-30.
	There is frequent osteosclerosis with or without plasmacytoma, hepatosplenomegaly and polycythaemia.