Panniculitis-induced localized lipodystrophy

Panniculitis-induced localized lipodystrophy is a rare, acquired, localized lipodystrophy disorder characterized by eruption of tender, occasionally painful, erythematous nodules and plaques which enlarge radially and resolve into lipoatrophic lesions, often located in the upper and lower limbs. Histologically, lesions are characterized by lipophagic, lobular panniculitis and absence of vasculitis.

Antinuclear antibody positivity

The presence of autoantibodies in the serum that react against nuclei or nuclear components.


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PMID (PMCID)