Wilson disease

Wilson disease is a very rare inherited multisystemic disease presenting non-specific neurological, hepatic, psychiatric or osseo-muscular manifestations due to excessive copper deposition in the body.

Kayser-Fleischer ring

Grey-green or brownish-pigmented ring in the deep epithelial layers at the outer border of the cornea.


Total: 11

                       


(per page)
PMID (PMCID)
27869428
 MALE Child
[Hemolytic anemia as the first clinical presentation of Wilson disease: a pediatric case].
Henao C JA, Valverde Munoz K, Avila A ML.
Arch Argent Pediatr. 2016;114(6):e436-e439.
The possibility of Wilson disease was considered, which was confirmed with the finding of a Kayser-Fleischer ring in the eye exam.
22718296
 MALE Child
Liver structures of a patient with idiopathic copper toxicosis.
Hayashi H, Shinohara T, Goto K, Fujita Y, Murakami Y, Hattori A, Tatsumi Y, Shimizu A, Ichiki T.
Med Mol Morphol. 2012;45(2):105-9.
Because urinary copper excretion was increased, Wilson disease was highly suspected, but the serum level of ceruloplasmin was normal, and Kayser-Fleischer rings were not detected by slit lamp examination.
21901661
 FEMALE
Atypical presentation of Wilson disease.
Wadera S, Magid MS, McOmber M, Carpentieri D, Miloh T.
Semin Liver Dis. 2011;31(3):319-26.
Diagnosis of Wilson disease was further established based on the low serum ceruloplasmin, increased urinary and hepatic copper and presence of Kayser-Fleischer rings.
15909172
 MALE Child
Acute putaminal necrosis and white matter demyelination in a child with subnormal copper metabolism in Wilson disease: MR imaging and spectroscopic findings.
Juan CJ, Chen CY, Liu YJ, Chung HW, Chin SC, Hsueh CJ, Chu H, Zimmerman RA.
Neuroradiology. 2005;47(6):401-5.
Wilson disease (WD) that manifests solely with acute and severe neurological damage in the absence of hepatic disease and Kayser-Fleischer ring of the cornea is rare and difficult to diagnose at the acute setting.
12036681
 FEMALE
Kayser-Fleischer ring as the presenting sign of Wilson disease.
Liu M, Cohen EJ, Brewer GJ, Laibson PR.
Am J Ophthalmol. 2002;133(6):832-4.
To describe a case in which the recognition by the ophthalmologist of Kayser-Fleischer rings played a crucial role in the diagnosis of Wilson disease (hepatolenticular degeneration).
12036681
 FEMALE
Kayser-Fleischer ring as the presenting sign of Wilson disease.
Liu M, Cohen EJ, Brewer GJ, Laibson PR.
Am J Ophthalmol. 2002;133(6):832-4.
Kayser-Fleischer ring as the presenting sign of Wilson disease.
12036681
 FEMALE
Kayser-Fleischer ring as the presenting sign of Wilson disease.
Liu M, Cohen EJ, Brewer GJ, Laibson PR.
Am J Ophthalmol. 2002;133(6):832-4.
To describe a case in which the recognition by the ophthalmologist of Kayser-Fleischer rings played a crucial role in the diagnosis of Wilson disease (hepatolenticular degeneration).
8780087
 FEMALE Adult
Neurologic presentation of Wilson disease without Kayser-Fleischer rings.
Demirkiran M, Jankovic J, Lewis RA, Cox DW.
Neurology. 1996;46(4):1040-3.
Neurologic presentation of Wilson disease without Kayser-Fleischer rings.
1870819
 FEMALE Infant, Newborn
Recurrent abortion and the diagnosis of Wilson disease.
Schagen van Leeuwen JH, Christiaens GC, Hoogenraad TU.
Obstet Gynecol. 1991;78(3 Pt 2):547-9.
Wilson disease was diagnosed when Kayser-Fleischer rings were detected in the cornea.
3361051
 MALE Adult
Wilson's disease.
Finley TP.
J Am Optom Assoc. 1988;59(2):119-20.
Confirmation of Kayser-Fleischer rings on the cornea greatly assisted in the final diagnosis of Wilson's disease (hepatolenticular degeneration).
47714
 FEMALE Adult
Kayser-Fleischer ring and associated cataract in Wilson's disease.
Tso MO, Fine BS, Thorpe HE.
Am J Ophthalmol. 1975;79(3):479-88.
A 22-year-old woman with hepatolenticular degeneration, or Wilson's disease, was note clinically to have Kayser-Fleischer rings and associated cataracts.