Xeroderma pigmentosum

Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by extreme sensitivity to ultraviolet (UV)-induced changes in the skin and eyes, and multiple skin cancers. It is subdivided into 8 complementation groups, according to the affected gene: classical XP (XPA to XPG) and XP variant (XPV) (see these terms).

Papule

A circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point.


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PMID (PMCID)
7416797
MALE Child
Xeroderma pigmentosum. Ultrastructural study with special reference to abnormalities of the melanin pigmentary system.
Perrot H, Ortonne JP.
Arch Dermatol Res. 1980;268(1):43-51.
Unusual changes in the melanin pigmentary system were observed on a warty papule biopsy taken from a patient with xeroderma pigmentosum (XP).