Sheehan syndrome

Sheehan syndrome is a rare, acquired, pituitary hormone deficiency disorder resulting from pituitary necrosis following peri- or postpartum hemorrhage characterized by various symptoms depending on resulting hormone decrease (e.g. failure or difficulty with lactation, oligo- or amenorrhea, hot flashes, decreased libido, weakness, fatigue, anorexia, nausea, vomiting, hypoglycemia, hyponatremia, dizziness, decreased muscle mass, adrenal crisis). Secondary hypothyroidism and secondary adrenal insufficiency may also be presenting signs.

Polyuria

An increased rate of urine production.

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PMID (PMCID)
21041172	FEMALE	Adult
	Sheehan syndrome presenting as central diabetes insipidus: a rare presentation of an uncommon disorder.
	Kumar S, Burrows D, Dang S, Simmons D. Endocr Pract. 2011;17(1):108-14.
	It is important to consider posterior pituitary ischemia resulting from Sheehan syndrome presenting as central diabetes insipidus as a cause of polyuria because appropriate hormonal replacement initiated early can possibly improve clinical status and patient outcomes.