Oromandibular dystonia

A form of focal dystonia, affecting the lower part of the face and jaws. It is characterized by sustained or repetitive involuntary jaw and tongue movements and facial grimacing caused by involuntary spasms of the masticatory, facial, pharyngeal, lingual, and lip muscles.

Blepharospasm

A focal dystonia that affects the muscles of the eyelids and brow, associated with involuntary recurrent spasm of both eyelids.


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PMID (PMCID)
28424916
 MALE
Bilateral pallidotomy for Meige syndrome.
Minkin K, Gabrovski K, Dimova P, Tanova R, Penkov M, Todorov Y, Romansky K.
Acta Neurochir (Wien). 2017;159(7):1359-1363.
Meige syndrome (MS) is usually described as a combination of blepharospasm with oromandibular dystonia.
28659707
(5479101)
 OTHER
Meige's syndrome.
Gautam P, Bhatia MS, Kaur J, Rathi A.
Ind Psychiatry J. 2016;25(2):232-233.
Meige's syndrome consists of idiopathic blepharospasm and oromandibular dystonia.
25951177
 MIXED_SAMPLE Adult
Oral methylphenidate for the treatment of refractory facial dystonias.
Eftekhari K, Choe CH, Vagefi MR, Gausas RE, Eckstein LA.
Ophthalmic Plast Reconstr Surg. 2015;31(3):e65-6.
This series presents 3 patients with refractory periorbital and facial dystonias, including blepharospasm, apraxia of eyelid opening, and oromandibular dystonia unresponsive to standard treatments who experienced a response to oral methylphenidate therapy.
28360708
 OTHER
Tardive Blepharospasm and Meige Syndrome during Treatment with Quetiapine and Olanzapine.
Kilic A, Erten E, Ozdemir A.
Noro Psikiyatr Ars. 2015;52(2):207-209.
Meige syndrome, which has been presented in tardive syndromes, is a form of blepharospasm accompanied by oromandibular dystonia with manifestations over the face, jaw, and neck.
24249940
(3821215)
 OTHER
Meige's Syndrome: Rare Neurological Disorder Presenting as Conversion Disorder.
Debadatta M, Mishra AK.
Indian J Psychol Med. 2013;35(3):317-8.
A 35-year-old female presented to psychiatric department with blepharospasm and oromandibular dystonia with clinical provisional diagnosis of psychiatric disorder (Conversion Disorder).
24249940
(3821215)
 OTHER
Meige's Syndrome: Rare Neurological Disorder Presenting as Conversion Disorder.
Debadatta M, Mishra AK.
Indian J Psychol Med. 2013;35(3):317-8.
Meige's syndrome is a rare neurological syndrome characterized by oromandibular dystonia and blepharospasm.
21808480
(3141480)
 OTHER
Tardive Meige's syndrome associated with olanzapine.
Aggarwal A, Jain M, Khandelwal A, Jiloha RC.
Ann Indian Acad Neurol. 2011;14(2):133-4.
Meige's syndrome is characterized by blepharospasm and oromandibular dystonia.
20061080
 FEMALE Middle Aged
Meige's syndrome: A cranial dystonia treated with bilateral pallidal deep brain stimulation.
Markaki E, Kefalopoulou Z, Georgiopoulos M, Paschali A, Constantoyannis C.
Clin Neurol Neurosurg. 2010;112(4):344-6.
Meige's syndrome is a rare form of segmental dystonia characterized by blepharospasm and oromandibular dystonia.
15133826
 MALE Adult
Dystonia as a presenting sign of spinocerebellar ataxia type 1.
Wu YR, Lee-Chen GJ, Lang AE, Chen CM, Lin HY, Chen ST.
Mov Disord. 2004;19(5):586-7.
We report on a 39-year-old man who presented initially with marked blepharospasm, oromandibular dystonia and retrocollis and one year later developed mild ataxia.
15382486
 FEMALE Middle Aged
[Posterior laryngeal stenosis in patient with Meige's Syndrome].
Pino Rivero V, Marcos Garcia M, Trinidad Ruiz G, Pardo Romero G, Gonzalez Palomino A, Blasco Huelva A.
An Otorrinolaringol Ibero Am. 2004;31(4):349-54.
Meige's Syndrome is a combination of blepharospasm and oromandibular dystonia (cranial dystonia) that can affect the pharyngeal and respiratory musculature.
14513166
 MIXED_SAMPLE Middle Aged
[Botulinum toxin type B in the management of dystonia non-responsive to botulinum toxin type A].
Cardoso F.
Arq Neuropsiquiatr. 2003;61(3A):607-10.
Five years later he also presented with blepharospasm and idiopathic oromandibular dystonia.
11383945
 FEMALE Middle Aged
Meige syndrome secondary to basal ganglia injury: a potential cause of acute respiratory distress.
Kirton CA, Riopelle RJ.
Can J Neurol Sci. 2001;28(2):167-73.
Meige syndrome is a movement disorder that includes blepharospasm and oromandibular dystonias.
11280356
 FEMALE
Oral rehabilitation with osseointegrated implants in a patient with oromandibular dystonia with blepharospasm (Brueghel's syndrome): a patient history.
Penarrocha M, Sanchis JM, Rambla J, Sanchez MA.
Int J Oral Maxillofac Implants. 2001;16(1):115-7.
Oral rehabilitation with osseointegrated implants in a patient with oromandibular dystonia with blepharospasm (Brueghel's syndrome): a patient history.
11280356
 FEMALE
Oral rehabilitation with osseointegrated implants in a patient with oromandibular dystonia with blepharospasm (Brueghel's syndrome): a patient history.
Penarrocha M, Sanchis JM, Rambla J, Sanchez MA.
Int J Oral Maxillofac Implants. 2001;16(1):115-7.
Oromandibular dystonia with blepharospasm (also known as Brueghel's syndrome, Meige's syndrome, or idiopathic orofacial dystonia) is characterized by intense and involuntary spasms of the orofacial muscles, with a frequent loss of teeth and occlusal alterations that worsen the dystonic manifestations and cause mucosal lesions that can lead to complete edentulism.
9766696
 FEMALE Middle Aged
Neuroleptic-induced Meige's syndrome following akathisia: pharmacologic characteristics.
Hayashi T, Furutani M, Taniyama J, Kiyasu M, Hikasa S, Horiguchi J, Yamawaki S.
Psychiatry Clin Neurosci. 1998;52(4):445-8.
A 52-year-old schizophrenic patient acutely showed blepharospasm and oromandibular dystonia following neuroleptic-induced akathisia.
9766696
 FEMALE Middle Aged
Neuroleptic-induced Meige's syndrome following akathisia: pharmacologic characteristics.
Hayashi T, Furutani M, Taniyama J, Kiyasu M, Hikasa S, Horiguchi J, Yamawaki S.
Psychiatry Clin Neurosci. 1998;52(4):445-8.
Two days after the appearance of akathisia, blepharospasm and oromandibular dystonia appeared.
8997156
 MIXED_SAMPLE Middle Aged
Adult-onset focal dystonias: presentation and treatment options.
Esper GJ, Charles PD, Davis TL, Robertson D.
Tenn Med. 1997;90(1):18-20.
Most of the focal dystonias include cervical dystonia, blepharospasm, oromandibular dystonia, spasmodic dysphonia, and limb dystonia, specifically writer's cramp.
8226604
 FEMALE Adult
Meige's syndrome.
Verma RK, Gupta BK, Kochar SK, Poonia A, Kochar DK.
J Assoc Physicians India. 1993;41(3):173-4.
A case of Meige's syndrome is reported who presented with blepharospasm and oromandibular dystonia along with dislocation of jaw, due to severe dystonia.
2072526
 FEMALE Middle Aged
[Three cases of Meige syndrome treated with facial nerve block].
Matoba M, Niwa K, Takada M, Kameue T, Takeda Y, Ogiwara M, Ogawa H.
Masui. 1991;40(5):816-20.
All patients suffered from abnormal facial movement characterized by blepharospasm and oromandibular dystonia, and had atrophic changes of bilateral basal ganglia which were recognized by brain CT scan.
2254604
 FEMALE Middle Aged
Blepharospasm-oromandibular dystonia associated with a left cerebellopontine angle meningioma.
Persing JA, Muir A, Becker DG, Jankovic JJ, Anderson RL, Edlich RF.
J Emerg Med. 1990;8(5):571-4.
Blepharospasm-oromandibular dystonia is characterized by the presence of spasms of the orbicularis oculi (blepharospasm) and of the lower facial or oromandibular muscles.