Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum

Toxic epidermal necrolysis (TEN) is an acute and severe skin disease with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes.

Eczema

Eczema is a form of dermatitis. The term eczema is broadly applied to a range of persistent skin conditions and can be related to a number of underlying conditions. Manifestations of eczema can include dryness and recurring skin rashes with redness, skin edema, itching and dryness, crusting, flaking, blistering, cracking, oozing, or bleeding.


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(per page)
PMID (PMCID)
30169429
MIXED_SAMPLE
Anti-programmed cell death-1 therapy-associated bullous disorders: a systematic review of the literature.
Zhao CY, Hwang SJE, Consuegra G, Chou S, Fernandez-Penas P.
Melanoma Res. 2018;28(6):491-501.
Bullous disorders under anti-PD1 may be classified clinically as BP, SJS/TEN/EM, bullous lichenoid reactions and vesiculobullous eczema and histologically by intraepidermal splitting and subepidermal splitting.