Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Skin rash

A red eruption of the skin.


Total: 7

                      


(per page)
PMID (PMCID)
30665484
FEMALE Middle Aged
Necrolytic Migratory Erythema: Complete Healing after Surgical Removal of Pancreatic Carcinoma.
V'lckova-Laskoska M, Balabanova-Stefanova M, Arsovska-Bezhoska I, Caca-Biljanovska N, Laskoski D.
Acta Dermatovenerol Croat. 2018;26(4):329-332.
The rarity of glucagonoma imposes a challenge, with most patients being diagnosed after a long period of treatment for their skin rash.
26981306
(4769757)
OTHER
Glucagonoma and Glucagonoma Syndrome: A Case Report with Review of Recent Advances in Management.
Al-Faouri A, Ajarma K, Alghazawi S, Al-Rawabdeh S, Zayadeen A.
Case Rep Surg. 2016;2016:1484089.
The rarity of glucagonoma imposes a challenge with most patients being diagnosed after a long period of treatment for their skin rash (months-years).
2703119
MALE Middle Aged
Necrolytic migratory erythema with elevated plasma enteroglucagon in celiac disease.
Kelly CP, Johnston CF, Nolan N, Keeling PW, Weir DG.
Gastroenterology. 1989;96(5 Pt 1):1350-3.
Necrolytic migratory erythema is the distinctive skin rash of the glucagonoma syndrome.
6326336
FEMALE
Glucagonoma occurring as a large cystic abdominal mass.
Ho PW, Moore GW, Hoge AF.
South Med J. 1984;77(5):666.
Glucagonoma syndrome should be considered in the differential diagnosis of a large abdominal mass even if skin rash is minimal.
111595
MALE Middle Aged
Amino acid deficiency and the skin rash associated with glucagonoma.
Norton JA, Kahn CR, Schiebinger R, Gorschboth C, Brennan MF.
Ann Intern Med. 1979;91(2):213-5.
Amino acid deficiency and the skin rash associated with glucagonoma.
111595
MALE Middle Aged
Amino acid deficiency and the skin rash associated with glucagonoma.
Norton JA, Kahn CR, Schiebinger R, Gorschboth C, Brennan MF.
Ann Intern Med. 1979;91(2):213-5.
These findings suggest that the skin rash associated with a glucagonoma is most likely due to an amino acid deficiency and can be reversed by parenteral nutrition.
111595
MALE Middle Aged
Amino acid deficiency and the skin rash associated with glucagonoma.
Norton JA, Kahn CR, Schiebinger R, Gorschboth C, Brennan MF.
Ann Intern Med. 1979;91(2):213-5.
To test the hypothesis that the skin rash associated with a glucagonoma is secondary to an amino acid deficiency, we obtained 2 d of fasting baseline laboratory data from the patient while he consumed his usual diet.