Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Obesity

Accumulation of substantial excess body fat.


Total: 4

                       


(per page)
PMID (PMCID)
26424307
 MALE Adult
A Novel Missense Mutation of the MEN1 Gene in a Patient with Multiple Endocrine Neoplasia Type 1 with Glucagonoma and Obesity.
Murakami T, Usui T, Nakajima A, Mochida Y, Saito S, Nambu T, Kato T, Matsuda Y, Yonemitsu S, Muro S, Oki S.
Intern Med. 2015;54(19):2475-81.
A Novel Missense Mutation of the MEN1 Gene in a Patient with Multiple Endocrine Neoplasia Type 1 with Glucagonoma and Obesity.
26424307
 MALE Adult
A Novel Missense Mutation of the MEN1 Gene in a Patient with Multiple Endocrine Neoplasia Type 1 with Glucagonoma and Obesity.
Murakami T, Usui T, Nakajima A, Mochida Y, Saito S, Nambu T, Kato T, Matsuda Y, Yonemitsu S, Muro S, Oki S.
Intern Med. 2015;54(19):2475-81.
However, he did not demonstrate weight loss, suggesting that the patient's obesity could have obscured the early diagnosis of a glucagonoma.
2848156
 FEMALE Adult
Glucagonoma presenting as morbid obesity.
Martin FM, Hamilton W, Dons R, Cashell AW, Ghosh BC.
J Surg Oncol. 1988;39(4):256-9.
Glucagonoma presenting as morbid obesity.
2848156
 FEMALE Adult
Glucagonoma presenting as morbid obesity.
Martin FM, Hamilton W, Dons R, Cashell AW, Ghosh BC.
J Surg Oncol. 1988;39(4):256-9.
A case is described that represents the only reported patient with glucagonoma syndrome and morbid obesity.