Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Anemia

A reduction in erythrocytes volume or hemoglobin concentration.


Total: 29

                      


(per page)
PMID (PMCID)
23890147
FEMALE Middle Aged
Necrolytic migratory erythema and glucagonoma rising from pancreatic head.
Tseng HC, Liu CT, Ho JC, Lin SH.
Pancreatology. 2013;13(4):455-7.
Glucagonoma syndrome encompasses necrolytic migratory erythema (NME), hyperglucagonemia, diabetes mellitus, anemia, weight loss, glossitis, angular cheilitis, steatorrhea, diarrhea, venous thrombosis, and neuropsychiatric disturbance.
23644134
MALE Middle Aged
[Diagnosis and treatment of glucagonoma: report of one case].
Cheng H, Chen M, Yang G.
Nan Fang Yi Ke Da Xue Xue Bao. 2013;33(4):618-insidebackcover.
We report a case of glucagonoma in a 55-year-old male patient with such clinical findings of necrolytic migratory erythema, diabetes mellitus, body weight loss, and anemia.
20465606
MALE
Glucagonoma syndrome and necrolytic migratory erythema.
Lobo I, Carvalho A, Amaral C, Machado S, Carvalho R.
Int J Dermatol. 2010;49(1):24-9.
The glucagonoma syndrome is a rare disorder, characterized by necrolytic migratory erythema, elevated serum glucagon levels, abnormal glucose tolerance, weight loss, and anemia in association with a glucagon-secreting alpha-cell tumor of the pancreas.
17926496
FEMALE Middle Aged
[A case of pancreatic glucagonoma].
Simonenko VB, Dulin PA, Beliaev LB, Makanin MA, Dem'ianenko AV, Zykova AA, Zhuravleva SI, Kolesnikova VN.
Klin Med (Mosk). 2007;85(8):67-70.
Glucagonoma syndrome is a disease that has an original clinical picture that includes necrolytic migrating erythema with secondary bullous dermatitis, glucose tolerance disorder or diabetes mellitus, weight loss, anemia, hypoaminoacidemia, venous thrombosis, and alimentary and mental disturbances.
15959605
MALE Middle Aged
Rare presentation of endocrine pancreatic tumor: a case of diffuse glucagonoma without metastasis and necrolytic migratory erythema.
Chen HW, Chen HW, Su DH, Shun CT, Liu KL.
J Formos Med Assoc. 2005;104(5):363-6.
We report a case of diffuse glucagonoma necrolytic migratory erythema (NME) in a 45-year-old man with mild diabetes mellitus, mild anemia, and weight loss over 1.5 years.
16476361
FEMALE Middle Aged
[Necrolytic migratory erythema associated with glucagonoma].
Mendoza-Guil F, Hernandez-Jurado I, Burkhardt P, Linares J, Naranjo R.
Actas Dermosifiliogr. 2005;96(3):175-8.
Glucagonoma is a rare pancreatic tumor that is usually associated with a syndrome that includes diabetes, anemia, weight loss and skin lesions in the form of necrolytic migratory erythema.
15313692
MALE Middle Aged
Clinical experience in diagnosis and treatment of glucagonoma syndrome.
Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS.
Hepatobiliary Pancreat Dis Int. 2004;3(3):473-5.
The clinical data of a case of pancreatic head tumor with typical glucagonoma syndrome of necrolytic migratory erythema (NME), diabetes mellitus (DM), anemia, and glossitis were retrospectively analyzed.
12918465
MALE
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
Koike N, Hatori T, Imaizumi T, Harada N, Fukuda A, Takasaki K, Iwamoto Y.
J Hepatobiliary Pancreat Surg. 2003;10(1):101-5.
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
12918465
MALE
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
Koike N, Hatori T, Imaizumi T, Harada N, Fukuda A, Takasaki K, Iwamoto Y.
J Hepatobiliary Pancreat Surg. 2003;10(1):101-5.
Therefore, we recommend checking patients who have diabetes mellitus and anemia in order to diagnose and treat glucagonoma in its early stage.
12918465
MALE
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
Koike N, Hatori T, Imaizumi T, Harada N, Fukuda A, Takasaki K, Iwamoto Y.
J Hepatobiliary Pancreat Surg. 2003;10(1):101-5.
We report the case of a 68-year-old Japanese man who underwent curative resection for malignant glucagonoma of the pancreas diagnosed through anemia and diabetes mellitus.
12918465
MALE
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
Koike N, Hatori T, Imaizumi T, Harada N, Fukuda A, Takasaki K, Iwamoto Y.
J Hepatobiliary Pancreat Surg. 2003;10(1):101-5.
The case of glucagonoma reported here was found through diagnostic examinations of anemia and treated by surgical resection, by which the patient's anemia was largely alleviated.
12918465
MALE
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
Koike N, Hatori T, Imaizumi T, Harada N, Fukuda A, Takasaki K, Iwamoto Y.
J Hepatobiliary Pancreat Surg. 2003;10(1):101-5.
The case of glucagonoma reported here was found through diagnostic examinations of anemia and treated by surgical resection, by which the patient's anemia was largely alleviated.
12918465
MALE
Malignant glucagonoma of the pancreas diagnoses through anemia and diabetes mellitus.
Koike N, Hatori T, Imaizumi T, Harada N, Fukuda A, Takasaki K, Iwamoto Y.
J Hepatobiliary Pancreat Surg. 2003;10(1):101-5.
Glucagonoma of the pancreas is a rare tumor with distinct clinical manifestations, such as necrolytic migratory erythema,weight loss, anemia, diabetes mellitus, and hypoamino-acidemia.
15037834
MALE
[Necrolytic migratory erythema revealing glucagonoma without diabetes].
Marty C, Bennet A, Bayle P, Danjoux M, Lalande T, Marguery MC, Bazex J.
Ann Med Interne (Paris). 2003;154(8):552-6.
We report a case of glucagonoma syndrome, revealed by a necrolytic migratory erythema that had developed for four Years, associated with anorexia, severe weight loss, anemia, hypoprotidemia, and hypoaminoacidemia.
11941895
FEMALE Middle Aged
Dermatitis, glossitis, stomatitis, cheilitis, anemia and weight loss: a classic presentation of pancreatic glucagonoma.
Povoski SP, Zaman SA, Ducatman BS, McFadden DW.
W V Med J. 2002;98(1):12-4.
Dermatitis, glossitis, stomatitis, cheilitis, anemia and weight loss: a classic presentation of pancreatic glucagonoma.
11836542
FEMALE Middle Aged
Necrolytic migratory erythema associated with glucagonoma syndrome: a case report.
Dal Coleto CC, de Mello AP, Piquero-Casals J, Lima FR, Vilela MA, Festa-Neto C, Sanches JA Jr.
Rev Hosp Clin Fac Med Sao Paulo. 2001;56(6):183-8.
It usually occurs in patients with an alpha islet cell tumor of the pancreas-or glucagonoma-and when associated with glucose intolerance, anemia, hyperglucagonemia, and weight loss defines the glucagonoma syndrome.
11836542
FEMALE Middle Aged
Necrolytic migratory erythema associated with glucagonoma syndrome: a case report.
Dal Coleto CC, de Mello AP, Piquero-Casals J, Lima FR, Vilela MA, Festa-Neto C, Sanches JA Jr.
Rev Hosp Clin Fac Med Sao Paulo. 2001;56(6):183-8.
It usually occurs in patients with an alpha islet cell tumor of the pancreas-or glucagonoma-and when associated with glucose intolerance, anemia, hyperglucagonemia, and weight loss defines the glucagonoma syndrome.
10502856
MALE Middle Aged
Glucagonoma syndrome: a case report.
Shyr YM, Su CH, Lee CH, Wu CW, Lui WY.
Zhonghua Yi Xue Za Zhi (Taipei). 1999;62(9):639-43.
We present a case of pancreatic tail tumor with the typical glucagonoma syndrome of necrolytic migratory erythema (NME), diabetes mellitus (DM), anemia, weight loss and glossitis.
9927793
MALE
[Pancreatic glucagonoma and deep vein thrombosis].
Guilarte Lopez-Manas J, Bellot Garcia V, Fernandez Perez R, Caballero Plasencia A.
Gastroenterol Hepatol. 1998;21(10):483-5.
Glucagonoma is an endocrine tumor of almost exclusively pancreatic origin which is rarely associated with a clinical syndrome mainly characterized by migratory necrolytic erythema, hyperglycemia, weight loss, hypoaminoacidemia and anemia.
9201330
MALE Adult
[Glucagonoma: case report and literature review].
das Neves MM, Martins Junior EV, Gaburri AK, Chebli JM, Stavale JN, Herani Filho AK.
Arq Gastroenterol. 1996;33(3):167-72.
Glucagonoma is a neuroendocrine tumor of pancreatic alpha cells manifested by necrolytic migratory erythema, hyperglucagonemia, glucose intolerance, weight loss, anemia and hypopaminoacidemia.