Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Diarrhea

Abnormally increased frequency of loose or watery bowel movements.


Total: 3

                       


(per page)
PMID (PMCID)
23890147
 FEMALE Middle Aged
Necrolytic migratory erythema and glucagonoma rising from pancreatic head.
Tseng HC, Liu CT, Ho JC, Lin SH.
Pancreatology. 2013;13(4):455-7.
Glucagonoma syndrome encompasses necrolytic migratory erythema (NME), hyperglucagonemia, diabetes mellitus, anemia, weight loss, glossitis, angular cheilitis, steatorrhea, diarrhea, venous thrombosis, and neuropsychiatric disturbance.
2847862
 MALE Middle Aged
A combined glucagonoma and VIPoma syndrome. First pathologic and clinical report.
Cavallo-Perin P, De Paoli M, Guiso G, Sapino A, Papotti M, Coda R, Pagano G.
Cancer. 1988;62(12):2576-9.
We report a case of pancreatic tumour metastatic to the liver in a patient with insulin-treated diabetes, anaemia, cheilitis, necrolytic migratory erythema, hypokalemia and chronic watery diarrhea, a picture suggesting combined glucagonoma and VIPoma syndromes.
197871
 MALE Adult
[Islet cell tumor with diarrhea and diabetes (glucagonoma?) associated with hyperparathyroidism. Long-term results of local-regional treatment with streptozotocin].
Leclere J, Vicari F, Laurent J, Jeanpierre R, Floquet J, Grignon G, Hartemann P.
Ann Endocrinol (Paris). 1977;38(2):153-4.
[Islet cell tumor with diarrhea and diabetes (glucagonoma?)