Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Neoplasm of the pancreas

A tumor (abnormal growth of tissue) of the pancreas.


Total: 1

                       


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PMID (PMCID)
12917088
 MIXED_SAMPLE Middle Aged
Reproduction of features of the glucagonoma syndrome with continuous intravenous glucagon infusion as therapy for tumor-induced hypoglycemia.
Case CC, Vassilopoulou-Sellin R.
Endocr Pract. 2003;9(1):22-5.
These complications resemble symptoms that characterize the human model of hyperglucagonemia--the glucagonoma syndrome--which is associated with hyperglucagonemia and alpha-islet cell neoplasms of the pancreas.