Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Hypokalemia

An abnormally decreased potassium concentration in the blood.


Total: 2

                       


(per page)
PMID (PMCID)
2847862
 MALE Middle Aged
A combined glucagonoma and VIPoma syndrome. First pathologic and clinical report.
Cavallo-Perin P, De Paoli M, Guiso G, Sapino A, Papotti M, Coda R, Pagano G.
Cancer. 1988;62(12):2576-9.
We report a case of pancreatic tumour metastatic to the liver in a patient with insulin-treated diabetes, anaemia, cheilitis, necrolytic migratory erythema, hypokalemia and chronic watery diarrhea, a picture suggesting combined glucagonoma and VIPoma syndromes.
2873145
 FEMALE Middle Aged
[The glucagonoma syndrome. Review of the literature. Apropos of a case].
Penchet A, Olivier A, Passa P, Orsoni JL, Charleux H.
J Chir (Paris). 1986;123(3):157-63.
A patient with typical clinical and biochemical features of a glucagonoma also presented obvious signs of hypokalemia, indicating combined secretion of renin by the tumor.