Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Pancreatic endocrine tumor

A neuroendocrine tumor originating in a hormone-producing cell (islet cell) of the pancreas.


Total: 5

                      


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PMID (PMCID)
19525592
FEMALE
Glucagonoma diagnosed by arterial stimulation and venous sampling (ASVS).
Okauchi Y, Nammo T, Iwahashi H, Kizu T, Hayashi I, Okita K, Yamagata K, Uno S, Katsube F, Matsuhisa M, Kato K, Aozasa K, Kim T, Osuga K, Nakamori S, Tamaki Y, Funahashi T, Miyagawa J, Shimomura I.
Intern Med. 2009;48(12):1025-30.
To identify the location of pancreatic endocrine tumors, arterial stimulation and venous sampling (ASVS) is known to be useful for insulinoma and gastrinoma, but its usefulness for glucagonoma has not been verified to date.
16443073
MALE Middle Aged
Metastatic glucagonoma: treatment with liver transplantation.
Radny P, Eigentler TK, Soennichsen K, Overkamp D, Raab HR, Viebahn R, Mueller-Horvart C, Sotlar K, Rassner G.
J Am Acad Dermatol. 2006;54(2):344-7.
Glucagonoma is a rare pancreatic endocrine tumor that is often both well developed and malignant at detection.
15313692
MALE Middle Aged
Clinical experience in diagnosis and treatment of glucagonoma syndrome.
Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS.
Hepatobiliary Pancreat Dis Int. 2004;3(3):473-5.
Pancreatic endocrine tumors are uncommon neoplasms and can lead to systemic disorder including glucagonoma syndrome, a very rare prototypical paraneoplastic phenomenon.
14598140
FEMALE Middle Aged
Laparoscopic resection for nonfunctioning small glucagon-producing tumor: report of a case and review of the literature.
Yada K, Hirano S, Himeno Y, Shibata K, Matsumoto T, Aramaki M, Kawano K, Kitano S.
J Hepatobiliary Pancreat Surg. 2003;10(5):382-5.
Glucagonoma is a relatively rare type of pancreatic endocrine tumor, and is often well-developed and malignant at detection.
2276959
MIXED_SAMPLE
Glucagon-producing pancreatic endocrine tumors in two dogs with superficial necrolytic dermatitis.
Gross TL, O'Brien TD, Davies AP, Long RE.
J Am Vet Med Assoc. 1990;197(12):1619-22.
Clinically and histologically, skin lesions closely resembled necrolytic migratory erythema of people, a skin disease that usually is associated with a glucagon-secreting pancreatic endocrine tumor and diabetes mellitus (glucagonoma syndrome): The morphologically descriptive term, superficial necrolytic dermatitis, was preferred over the previously proposed names hepatocutaneous syndrome and diabetic dermatopathy, which each connote only a single feature of the disease.