Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Carcinoma

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus).


Total: 8

                      


(per page)
PMID (PMCID)
30665484
FEMALE Middle Aged
Necrolytic Migratory Erythema: Complete Healing after Surgical Removal of Pancreatic Carcinoma.
V'lckova-Laskoska M, Balabanova-Stefanova M, Arsovska-Bezhoska I, Caca-Biljanovska N, Laskoski D.
Acta Dermatovenerol Croat. 2018;26(4):329-332.
After surgical removal of pancreatic carcinoma/glucagonoma, complete healing and a long disease-free period was achieved.
9756012
MALE Adult
Asymptomatic glucagonoma presenting with an isolated hepatic nodule.
De Giorgio R, Migliori M, Lalli S, Montini GC, Gullo L, Corinaldesi R, Bordi C, Tomassetti P.
Hepatogastroenterology. 1998;45(22):1093-6.
The concomitant presence of a glucagonoma and a carcinoma of the large intestine has not been previously reported, and its significance remains unclear.
8662436
MIXED_SAMPLE Adult
Sonographic features of liver metastases from pancreatic glucagonoma and acinar cell carcinoma. Case reports.
Ferrari A, Gavinelli M, Dominioni L, Carcano G, Dionigi R.
Surg Endosc. 1996;10(7):762-4.
Survival from diagnosis of liver metastases was 45 months in the patient with pancreatic glucagonoma and 23 months in the patient with acinar cell carcinoma.
6327570
MALE Middle Aged
[The glucagonoma syndrome--a not-so-well-known cutaneous paraneoplastic condition. Case report].
Galle K, Schweiss D.
Hautarzt. 1984;35(4):204-9.
Report on a 50-year-old patient suffering from glucagonoma-syndrome caused by a metastatic pancreatic islet cell carcinoma which produced several peptide hormones.
6267376
MIXED_SAMPLE Adult
Dimethyltriazenoimidazole carboxamide therapy of islet cell carcinoma of the pancreas.
Awrich AE, Peetz M, Fletcher WS.
J Surg Oncol. 1981;17(4):321-6.
Four patients with metastatic glucagonoma and one patient with metastatic diarrheogenic islet cell carcinoma of the pancreas were treated with dimethyltriazenoimidazole carboxamide (DTIC), 250 mg/M2 daily for five days repeated every four weeks.
6269242
MALE Middle Aged
Operative and chemotherapeutic management of malignant glucagon-producing tumors.
Prinz RA, Badrinath K, Banerji M, Sparagana M, Dorsch TR, Lawrence AM.
Surgery. 1981;90(4):713-9.
Two patients are described in whom the characteristic dermatitis, glucose intolerance, weight loss, and anemia of the glucagonoma syndrome were due to a metastasizing islet cell carcinoma.
228832
MALE Adult
Neurologic involvement in glucagonoma syndrome: response to combination chemotherapy with 5-fluorouracil and streptozotocin.
Khandekar JD, Oyer D, Miller HJ, Vick NA.
Cancer. 1979;44(6):2014-6.
The diagnosis of glucagonoma was made by light and electron microscopic demonstration of a metastatic alpha cell carcinoma in a liver biopsy specimen.
232767
MALE Middle Aged
[Cancer of the alpha cells of the pancreas].
Ramierz Arias JL, Anzures ME, Mercado Perez C, Rodriguez L, Albores J, Crotte A.
Rev Interam Radiol. 1979;4(1):33-6.
One of them is the so called alpha cell carcinoma also called glucagonoma usually associated with diabetes and skin lesions somewhat typical.