Glucagonoma

Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.

Cheilitis

Inflammation of the lip.


Total: 3

                       


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PMID (PMCID)
20499510
 FEMALE Adult
[Glucagonoma without glucagonoma syndrome].
Colovic R, Matic S, Micev M, Grubor N, Latincic S.
Srp Arh Celok Lek. 2010;138(3-4):244-7.
They usually secrete large amounts of glucagon that can cause a characteristic "glucagonoma syndrome", which includes necrolytic migratory erythema, glucose intolerance or diabetes, weight loss and sometimes, normochromic normocytic anaemia, stomatitis or cheilitis, diarrhoea or other digestive symptoms, thoromboembolism, hepatosplenomegaly, depression or other psychiatric and paraneoplastic symptoms.
11941895
 FEMALE Middle Aged
Dermatitis, glossitis, stomatitis, cheilitis, anemia and weight loss: a classic presentation of pancreatic glucagonoma.
Povoski SP, Zaman SA, Ducatman BS, McFadden DW.
W V Med J. 2002;98(1):12-4.
Dermatitis, glossitis, stomatitis, cheilitis, anemia and weight loss: a classic presentation of pancreatic glucagonoma.
2847862
 MALE Middle Aged
A combined glucagonoma and VIPoma syndrome. First pathologic and clinical report.
Cavallo-Perin P, De Paoli M, Guiso G, Sapino A, Papotti M, Coda R, Pagano G.
Cancer. 1988;62(12):2576-9.
We report a case of pancreatic tumour metastatic to the liver in a patient with insulin-treated diabetes, anaemia, cheilitis, necrolytic migratory erythema, hypokalemia and chronic watery diarrhea, a picture suggesting combined glucagonoma and VIPoma syndromes.