Somatostatinoma

Somatostatinoma (SSoma) is an extremely rare pancreatic neuroendocrine tumor or duodenal endocrine tumor (see these terms) that originates either in the pancreas (50%) or the gastrointestinal tract (50%) and mainly presents with non-specific symptoms of abdominal pain, weight loss, jaundice and diarrhea but, in approximately 20% of pancreatic cases, leads to a somatostatin hypersecretion syndrome (somatostatinoma syndrome) characterized by diabetes mellitus, cholelithiasis, steatorrhea and hypochlorhydria.

Jaundice

Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.


Total: 6

                       


(per page)
PMID (PMCID)
30635305
 FEMALE Adult
Duodenal somatostatinoma presenting as obstructive jaundice with the coexistence of a gastrointestinal stromal tumour in neurofibromatosis type 1: a case with review of the literature.
Thavaraputta S, Graham S, Rivas Mejia AM, Lado-Abeal J.
BMJ Case Rep. 2019;12(1):.
Duodenal somatostatinoma presenting as obstructive jaundice with the coexistence of a gastrointestinal stromal tumour in neurofibromatosis type 1: a case with review of the literature.
21209467
 MALE Middle Aged
A rare cause of obstructive jaundice and weight loss in Von Recklinghausen's disease.
Bukkems SF, Stoot JH, Driessen A, Beets-Tan RG, van Nieuwenhoven MA, Masclee AM.
Neth J Med. 2010;68(12):414-7.
The patient had recurrent jaundice, the typical somatostatinoma syndrome, positive MR imaging but negative 83108312Ga-DOTATOC PET scanning in a histopathology-proven somatostatinoma tumour.
21209467
 MALE Middle Aged
A rare cause of obstructive jaundice and weight loss in Von Recklinghausen's disease.
Bukkems SF, Stoot JH, Driessen A, Beets-Tan RG, van Nieuwenhoven MA, Masclee AM.
Neth J Med. 2010;68(12):414-7.
The patient had recurrent jaundice, the typical somatostatinoma syndrome, positive MR imaging but negative 83108312Ga-DOTATOC PET scanning in a histopathology-proven somatostatinoma tumour.
15258554
 FEMALE Adult
Von Recklinghausen's neurofibromatosis associated with duodenal somatostatinoma. A case report and review of the literature.
Cappelli C, Agosti B, Braga M, Cumetti D, Gandossi E, Rizzoni D, Agabiti Rosei E.
Minerva Endocrinol. 2004;29(1):19-24.
A case of a patient affected by VRNF associated with duodenal somatostatinoma with consequent obstructive jaundice is reported.
8654616
 FEMALE Adult
Ampullary somatostatinoma associated with von Recklinghausen's neurofibromatosis presenting as obstructive jaundice.
Tan CC, Hall RI, Semeraro D, Irons RP, Freeman JG.
Eur J Surg Oncol. 1996;22(3):298-301.
Ampullary somatostatinoma associated with von Recklinghausen's neurofibromatosis presenting as obstructive jaundice.
8654616
 FEMALE Adult
Ampullary somatostatinoma associated with von Recklinghausen's neurofibromatosis presenting as obstructive jaundice.
Tan CC, Hall RI, Semeraro D, Irons RP, Freeman JG.
Eur J Surg Oncol. 1996;22(3):298-301.
A case of von Recklinghausen's disease associated with a somatostatinoma of the pancreas causing obstructive jaundice is described.