Refractory anemia

Refractory cytopenias with unilineage dysplasia (RCUD) is a frequent low-risk subtype of myelodysplastic syndrome (MDS; see this term) characterized by refractory cytopenias associated with dysplasia limited to one cell lineage.

Anisocytosis

Abnormally increased variability in the size of erythrocytes.


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PMID (PMCID)
7071578
 FEMALE
[The 5q syndrome--a chromosome aberration with characteristic hematologic picture: preleukemia? Literature review and description of a personal case].
Mueller RA, Auf der Maur P, Beck EA, Deubelbeiss K, Bucher U.
Schweiz Med Wochenschr. 1982;112(7):242-52.
Hematologic changes are (1) macrocytic, refractory anemia, (2) low to normal leukocyte counts, (3) normal to increased platelet number with marked anisocytosis and a high proportion of megathrombocytes, (4) normal to hypoplastic erythropoiesis and generally small megakaryocytes with nonlobulated nuclei in the bone marrow.