Refractory anemia

Refractory cytopenias with unilineage dysplasia (RCUD) is a frequent low-risk subtype of myelodysplastic syndrome (MDS; see this term) characterized by refractory cytopenias associated with dysplasia limited to one cell lineage.

Myelofibrosis

Replacement of bone marrow by fibrous tissue.


Total: 5

                       


(per page)
PMID (PMCID)
8312669
 MIXED_SAMPLE Middle Aged
Myelodysplastic syndrome associated with myelofibrosis, a report of 3 cases.
Kamei S, Shinohara K, Oeda E.
Intern Med. 1993;32(8):668-71.
Three cases of primary myelodysplastic syndrome (MDS) associated with myelofibrosis were initially diagnosed as refractory anemia by the presence of bicytopenia or pancytopenia and having normo- or hypercellular marrow with dysplastic features.
1774954
 MIXED_SAMPLE Middle Aged
Extra translocation +der(1q9p) is a prognostic indicator in myeloproliferative disorders.
Rege-Cambrin G, Speleman F, Kerim S, Scaravaglio P, Carozzi F, Dal Cin P, Michaux JL, Offner F, Saglio G, Van den Berghe H.
Leukemia. 1991;5(12):1059-63.
Two patients had polycythemia vera in transformation (erythroleukemia in one patient and refractory anemia in the second), whereas the third patient had myelofibrosis which later evolved into acute myelomonocytic leukemia.
1942532
 MALE
[Myelodysplasia predominantly involving in megakaryocytic lineage successfully treated with low-dose Ara-C].
Tsushita K, Hotta T, Inoue C, Ichikawa A, Murate T, Saito H.
Rinsho Ketsueki. 1991;32(8):897-902.
Therefore he was diagnosed as refractory anemia (RA) or MDS with myelofibrosis and treated with low dose Ara-C regimen.
3279751
 MALE Middle Aged
Myelodysplastic syndrome with acquired hemoglobin H disease. Evolution through megakaryoblastic transformation into myelofibrosis.
Abbondanzo SL, Anagnou NP, Sacher RA.
Am J Clin Pathol. 1988;89(3):401-6.
Although idiopathic myelofibrosis also has been described as a setting in which this thalassemic syndrome occurs, the present case is unusual in that the myelofibrosis was preceded by refractory anemia with leukemic transformation.
3060251
 MIXED_SAMPLE Child
Translocation t(1;7) revisited. Report of three further cases and review.
Willem P, Pinto M, Bernstein R.
Cancer Genet Cytogenet. 1988;36(1):45-54.
Three white patients, two with myelofibrosis and one with refractory anemia, presented with a t(1;7).