Refractory anemia

Refractory cytopenias with unilineage dysplasia (RCUD) is a frequent low-risk subtype of myelodysplastic syndrome (MDS; see this term) characterized by refractory cytopenias associated with dysplasia limited to one cell lineage.

Erythroid hyperplasia

Increased count of erythroid precursor cells, that is, erythroid lineage cells in the bone marrow.


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PMID (PMCID)
9128421
 FEMALE Middle Aged
[A case of malignant rheumatoid arthritis associated with myelodysplastic syndrome].
Hisakawa N, Nishiya K, Hashimoto K, Tanaka Y.
Ryumachi. 1997;37(1):30-5.
The patient (57 year-old female) complained of high fever and polyarthralgia in autumn of 1994, when a diagnosis of refractory anemia, a type of myelodysplastic syndrome (MDS) was made by severe anemia (RBC: 154 x 10(4)/microliters), leucopenia (2,200/microliters) and erythroid hyperplasia, ring-nucleated myelocyte, micromegakaryocyte and less than 5% of blasts in bone marrow smear.
8589370
 MALE Middle Aged
Myelodysplastic syndrome associated with erythrophagocytosis by blasts and myeloid cells.
Kuyama J, Fushino M, Take H, Kanayama Y.
Int J Hematol. 1995;62(4):243-6.
A 63-year-old man with refractory anemia with excess of blasts in transformation exhibited erythroid hyperplasia, dyserythropoiesis, a del(20q) abnormality, susceptibility to bacterial infections, and a relatively short survival.