Refractory anemia

Refractory cytopenias with unilineage dysplasia (RCUD) is a frequent low-risk subtype of myelodysplastic syndrome (MDS; see this term) characterized by refractory cytopenias associated with dysplasia limited to one cell lineage.

Paraproteinemia

An abnormal immunoglobulin or part of an Ig (light chain) in the circulation. Paraproteins are typically produced by a clonal population of B-cell derived plasma cells.


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PMID (PMCID)
816450
 FEMALE Middle Aged
Acute myelomonocytic leukemia associated with paraproteinemia.
Law IP, Koch FJ, Cannon GB, Herberman RB, Oldham RK.
Cancer. 1976;37(3):1359-64.
A 49-year-old white woman with refractory anemia subsequently developed acute myelomonocytic leukemia with paraproteinemia 12 months later.