Acute myeloblastic leukemia without maturation

A rare, acute myeloid leukemia characterized by no significant myeloid maturation and more than 90% blast cells in the non-erythroid population. Various degrees of anemia, thrombocytopenia, or pancytopenia are present. Frequent clinical manifestations include fatigue, fever, bleeding disorders, and organomegaly, especially hepatosplenomegaly.

Thrombocytopenia

A reduction in the number of circulating thrombocytes.


Total: 1

                       


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PMID (PMCID)
12841385
 MIXED_SAMPLE Child
Two cases of acute myeloblastic leukemia evolving from aplastic anemia.
Taguchi A, Tominaga T, Nakamori Y, Miyazaki M, Shinohara K.
Int J Hematol. 2003;77(5):471-5.
Thrombocytopenia recurred and did not respond to cyclosporine and methenolone or to later treatment with antithymocyte globulin, and AML M1 developed.