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Acute myeloblastic leukemia without maturation

A rare, acute myeloid leukemia characterized by no significant myeloid maturation and more than 90% blast cells in the non-erythroid population. Various degrees of anemia, thrombocytopenia, or pancytopenia are present. Frequent clinical manifestations include fatigue, fever, bleeding disorders, and organomegaly, especially hepatosplenomegaly.

Eosinophilia

Increased count of eosinophils in the blood.

Total: 1

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PMID (PMCID)
9713991	MALE
	Rearrangement between the MYH11 gene at 16p13 and D12S158 at 12p13 in a case of acute myeloid leukemia M1 (AML-M1).
	La Starza R, Wlodarska I, Matteucci C, Falzetti D, Baens M, Martelli MF, Van den Berghe H, Marynen P, Mecucci C. Genes Chromosomes Cancer. 1998;23(1):10-5.
	A case of acute myeloid leukemia (AML) M1 with bone marrow eosinophilia was characterized by cytogenetics and fluorescence in situ hybridization (FISH).