Acute myeloblastic leukemia without maturation

A rare, acute myeloid leukemia characterized by no significant myeloid maturation and more than 90% blast cells in the non-erythroid population. Various degrees of anemia, thrombocytopenia, or pancytopenia are present. Frequent clinical manifestations include fatigue, fever, bleeding disorders, and organomegaly, especially hepatosplenomegaly.

Arrhythmia

Any cardiac rhythm other than the normal sinus rhythm. Such a rhythm may be either of sinus or ectopic origin and either regular or irregular. An arrhythmia may be due to a disturbance in impulse formation or conduction or both.


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PMID (PMCID)
1942537
FEMALE Adult
[Torsade de pointes ventricular tachycardia in a patient with acute myelocytic leukemia].
Morioka M, Kakinoki Y, Katagiri M, Iwasaki H, Gotohda Y, Kobayashi T, Tanaka M, Sakurada K, Miyazaki T.
Rinsho Ketsueki. 1991;32(9):1009-11.
We experienced Torsade-de-pointes arrhythmia during the treatment of acute myelocytic leukemia (AML); The patient was a 28 year old woman and had an AML-M1.