Aggressive systemic mastocytosis

A severe and rare form of systemic mastocytosis (SM) characterized by considerable infiltration of mast cells in different tissues.

Eosinophilia

Increased count of eosinophils in the blood.


Total: 2

                       


(per page)
PMID (PMCID)
24369222
 FEMALE Adult
Eosinophilia and bone lesion as clinical manifestations of aggressive systemic mastocytosis.
Sakane-Ishikawa E, Kodaka T, Tsunemine H, Itoh K, Akasaka H, Kusama T, Imaizumi K, Taketomi M, Sada A, Katayama Y, Itoh T, Takahashi T.
J Clin Exp Hematop. 2013;53(3):207-13.
Eosinophilia and bone lesion as clinical manifestations of aggressive systemic mastocytosis.
16506600
 FEMALE Middle Aged
[Isolated lymphadenopathy as the first presentation of systemic mastocytosis--description of two cases].
Kinkor Z, Sima R, Skalova A, Boudova L, Pekova S, Dvorakova D, Dedic K, Kracik M, Janousek M, Michal M.
Cesk Patol. 2006;42(1):34-8.
The first case was classified as a indolent systemic mastocytosis without any proven genetic alteration, the second one met the criteria of aggressive systemic mastocytosis with eosinophilia, where the point mutation asp816val in c-kit gene was confirmed and the patient responded unexpectedly well to Gleevec.