Congenital dyserythropoietic anemia type II

Congenital dyserythropoietic anemia type II (CDA II) is the most common form of CDA (see this term) characterized by anemia, jaundice and splenomegaly and often leading to liver iron overload and gallstones.

Jaundice

Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.


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PMID (PMCID)
11399576
 OTHER
Erythropoiesis: Case Report: Congenital Dyserythropoietic Anemia Type II in a Woman Presenting with Jaundice, Anemia, and Splenomegaly.
Abali H, Haznedaroglu IC, Sayinalp N, Kosar A, Buyukasik Y, Ozatli D, Batman F.
Hematology. 1999;4(4):357-360.
Erythropoiesis: Case Report: Congenital Dyserythropoietic Anemia Type II in a Woman Presenting with Jaundice, Anemia, and Splenomegaly.
11399576
 OTHER
Erythropoiesis: Case Report: Congenital Dyserythropoietic Anemia Type II in a Woman Presenting with Jaundice, Anemia, and Splenomegaly.
Abali H, Haznedaroglu IC, Sayinalp N, Kosar A, Buyukasik Y, Ozatli D, Batman F.
Hematology. 1999;4(4):357-360.
We herein report a case of CDA type II, who presents with a mild anemia, jaundice, splenomegaly, cholelithiasis and hemolysis.
514807
 MIXED_SAMPLE Child
Congenital dyserythropoietic anemia type II: serologic and morphologic family study.
Ricci P, Baccarani M, Biagini G, Preda P, Tomasini I, Zucchelli P, Tura S.
Nouv Rev Fr Hematol. 1979;21(2):197-207.
A 29-year old woman with a history of chronic anemia, jaundice, and splenectomy was found to have congenital dyserythropoietic anemia type II (CDA II), based on the following: marrow erythroid hyperplasia, abundance of binucleated erythroblasts, electron microscopic evidence of double membranes lining the cell membrane, erythrocyte lysis in the acidified serum test, erythrocyte agglutination and lysis by anti-i antibodies.
514807
 MIXED_SAMPLE Child
Congenital dyserythropoietic anemia type II: serologic and morphologic family study.
Ricci P, Baccarani M, Biagini G, Preda P, Tomasini I, Zucchelli P, Tura S.
Nouv Rev Fr Hematol. 1979;21(2):197-207.
A 29-year old woman with a history of chronic anemia, jaundice, and splenectomy was found to have congenital dyserythropoietic anemia type II (CDA II), based on the following: marrow erythroid hyperplasia, abundance of binucleated erythroblasts, electron microscopic evidence of double membranes lining the cell membrane, erythrocyte lysis in the acidified serum test, erythrocyte agglutination and lysis by anti-i antibodies.
1004360
 MIXED_SAMPLE Adult
[Congenital dyserythropoietic anemia type II. Another case report].
Hartwich G, Riemann J, Kronert E.
Med Klin. 1976;71(48):2117-22.
Hematologic evaluation of a 29-year old man with jaundice since childhood demonstrated the characteristic findings of congenital dyserythropoietic anemia (CDA) type II.