Pituitary gigantism

A rare endocrine disease characterized by unusually tall stature (with rapid growth velocity), occurring before closure of the epiphyseal growth plates, due to excessive growth hormone (GH) caused by a GH-secreting pituitary tumor or from pituitary hyperplasia. Additional associated features may include pubertal delay, visual defects, headache, excessive appetite, hyperhidrosis and menstrual irregularity, as well as variable manifestations characteristic of acromegaly, such as prognathism, coarse facial features and large hands/feet in adolescents.

Diabetes mellitus

A group of abnormalities characterized by hyperglycemia and glucose intolerance.


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(per page)
PMID (PMCID)
17629784
MALE
Management of type 2 diabetes mellitus associated with pituitary gigantism.
Ali O, Banerjee S, Kelly DF, Lee PD.
Pituitary. 2007;10(4):359-64.
Management of type 2 diabetes mellitus associated with pituitary gigantism.