Pituitary gigantism

A rare endocrine disease characterized by unusually tall stature (with rapid growth velocity), occurring before closure of the epiphyseal growth plates, due to excessive growth hormone (GH) caused by a GH-secreting pituitary tumor or from pituitary hyperplasia. Additional associated features may include pubertal delay, visual defects, headache, excessive appetite, hyperhidrosis and menstrual irregularity, as well as variable manifestations characteristic of acromegaly, such as prognathism, coarse facial features and large hands/feet in adolescents.

Cluster headache

A type of headache characterized by repeated attacks of unilateral pain lasting 15 to 180 minutes and associated with local autonomic signs.


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(per page)
PMID (PMCID)
15516776
MALE Adult
Long-term effects of octreotide on pituitary gigantism: its analgesic action on cluster headache.
Otsuka F, Mizobuchi S, Ogura T, Sato K, Yokoyama M, Makino H.
Endocr J. 2004;51(5):449-52.
Long-term effects of octreotide on pituitary gigantism: its analgesic action on cluster headache.