Hemophagocytic syndrome associated with an infection




Input patient's signs and symptoms


Narrow down the case reports



Total: 110 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
100
(9.2%)		 27496079
 Fulminant Epstein-Barr virus-associated hemophagocytic syndrome in a renal transplant patient and review of the literature.
Romiopoulos I, Pyrpasopoulou A, Onoufriadis I, Massa E, Mouloudi E, Kydona C, Giasnetsova T, Gerogianni N, Myserlis G, Solonaki F, Nikodimopoulou M, Mandala E, Antachopoulos C, Roilides E.
Transpl Infect Dis. 2016;18(5):795-800.
Sepsis
Antiviral Agents Combination Drug Therapy Diarrhea Epstein-Barr Virus Infections Fatal Outcome Females Fever Homo sapiens IGA Glomerulonephritis Immunocompromised Host Immunosuppressive Agents Kidney Transplantation Lymphohistiocytosis, Hemophagocytic Multiple Organ Failure Oliguria
100
(9.2%)		 22185972
 Repeated Epstein-Barr virus-associated hemophagocytic syndrome in a lupus nephritis patient.
Miura S, Takeda K, Muto Y, Mukai H, Furusho M, Nakashita S, Maeda A, Kimura H.
Clin Nephrol. 2012;77(1):71-4.
Nephrotic syndrome Nephritis
Antineoplastic Agents Epstein-Barr Virus Infections Females Homo sapiens Lupus Nephritis Lymphohistiocytosis, Hemophagocytic Middle Aged Remission Induction
100
(9.2%)		 15625619
 Epstein-Barr virus-associated hemophagocytic syndrome in a patient with lupus nephritis.
Isome M, Suzuki J, Takahashi A, Murai H, Nozawa R, Suzuki S, Kawasaki Y, Suzuki H.
Pediatr Nephrol. 2005;20(2):226-8.
Nephritis
Child Epstein-Barr Virus Infections Females Histiocytosis, Non-Langerhans-Cell Homo sapiens Immunosuppressive Agents Lupus Nephritis
100
(9.2%)		 9444599
 Host defensive, immunological, and microbiological observations of an early-onset periodontitis patient with virus-associated hemophagocytic syndrome.
Kono T, Takigawa M, Nishimura F, Takashiba S, Nakagawa M, Maeda H, Arai H, Nagai A, Kurihara H, Murayama Y.
J Periodontol. 1997;68(12):1223-30.
Periodontitis
CD4 CD8A IFNG IL1B IL2 IL2RB IL4 IL6 TNF
Aggressive Periodontitis Alveolar Bone Loss Antibodies, Bacterial Bacteria Cytomegalovirus Infections Follow-Up Studies Gingivitis HLA Antigens Herpesviridae Infections Histiocytosis, Non-Langerhans-Cell Homo sapiens Interleukin 2 Receptor Interleukin-1 Interleukin-2 Lymphocyte Subset Male Periodontal Pocket T-Lymphocyte Tumor Necrosis Factor-alpha Tumor Virus Infections
100
(9.2%)		 2550305
 Myocardial involvement due to a disseminated human cytomegalovirus infection in a heart transplant recipient. A case report.
Pucci A, Grasso M, Arbustini E.
G Ital Cardiol. 1989;19(3):230-3.
Pneumonia
Cardiomyopathies Child Cytomegalovirus Infections Heart Transplantation Homo sapiens Male Pulmonary Fibrosis
100
(9.2%)		 1623484
 Documentation of Burkitt lymphoma with t(8;14) (q24;q32) in X-linked lymphoproliferative disease.
Egeler RM, de Kraker J, Slater R, Purtilo DT.
Cancer. 1992;70(3):683-7.
Immunodeficiency
Burkitt Lymphoma Child, Preschool Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 8 Homo sapiens Infant Lymphoproliferative Disorders Male
107
(9.2%)		 17106167
 Virus associated hemophagocytic syndrome accompanied by acute respiratory failure caused by influenza A (H3N2).
Ando M, Miyazaki E, Hiroshige S, Ashihara Y, Okubo T, Ueo M, Fukami T, Sugisaki K, Tsuda T, Ohishi K, Yoshitake S, Noguchi T, Kumamoto T.
Intern Med. 2006;45(20):1183-6.
Dyspnea Myocarditis
Adult Antibodies, Viral Bronchi Carcinoma Combined Modality Therapy Females Granulocyte Colony-Stimulating Factor Homo sapiens Immunocompromised Host Immunosuppressive Agents Influenza Influenza A Virus, H3N2 Subtype Lymphohistiocytosis, Hemophagocytic Myocarditis Postoperative Complications Respiration, Artificial Respiratory Insufficiency Sulfonamides Tongue Neoplasms
108
(5.0%)		 19155518
 Unique phenotypes of C1s deficiency and abnormality caused by two compound heterozygosities in a Japanese family.
Abe K, Endo Y, Nakazawa N, Kanno K, Okubo M, Hoshino T, Fujita T.
J Immunol. 2009;182(3):1681-8.
Loss of consciousness
C1S
p|SUB|E|597|X p|SUB|G|630|E
Adult Alleles Child Codon, Nonsense Females Genetic Carrier Screening Genotype Homo sapiens Japan Male Missense Mutation Phenotype Point Mutation Sequence Deletion Single-Stranded Conformational Polymorphism
108
(5.0%)		 11749757
(2730277)
 Human herpesvirus 6-associated hemophagocytic syndrome in a healthy adult.
Tanaka H, Nishimura T, Hakui M, Sugimoto H, Tanaka-Taya K, Yamanishi K.
Emerg Infect Dis. 2002;8(1):87-8.
Respiratory distress
Adult Antibodies, Viral Erythrocytes Granulocyte Colony-Stimulating Factor Histiocytes Homo sapiens Male Pancytopenia Phagocytosis Respiratory Distress Syndrome Roseolovirus Infections Syndrome
108
(5.0%)		 11133747
 Lymphocytic vasculitis in X-linked lymphoproliferative disease.
Dutz JP, Benoit L, Wang X, Demetrick DJ, Junker A, de Sa D, Tan R.
Blood. 2001;97(1):95-100.
Bronchiectasis
CD8A KRT20 SH2D1A
CD8 Antigens Carrier Proteins Cytotoxic T-Lymphocytes DNA, Viral Endothelium, Vascular Fatal Outcome Females Genotype Homo sapiens Immunohistochemistry Infant Intracellular Signaling Peptides and Proteins Lymphoproliferative Disorders Male Molecular Sequence Data Point Mutation Polymerase Chain Reaction Sequence Analysis, DNA Signaling Lymphocytic Activation Molecule Associat... Vasculitis
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 42

HPO ID Term # of case reports
HP:0012156 Hemophagocytosis 9
HP:0001945 Fever 5
HP:0002090 Pneumonia 3
HP:0100806 Sepsis 3
HP:0001433 Hepatosplenomegaly 2
HP:0001875 Neutropenia 2
HP:0001876 Pancytopenia 2
HP:0002721 Immunodeficiency 2
HP:0002840 Lymphadenitis 2
HP:0002878 Respiratory failure 2
HP:0012115 Hepatitis 2
HP:0032204 Chronic active Epstein-Barr virus infection 2
HP:0100727 Histiocytosis 2
HP:0200119 Acute hepatitis 2
HP:0000112 Nephropathy 1
HP:0000123 Nephritis 1
HP:0000704 Periodontitis 1
HP:0000952 Jaundice 1
HP:0000979 Purpura 1
HP:0000988 Skin rash 1
HP:0001251 Ataxia 1
HP:0001287 Meningitis 1
HP:0001744 Splenomegaly 1
HP:0001880 Eosinophilia 1
HP:0001903 Anemia 1
HP:0001909 Leukemia 1
HP:0001919 Acute kidney injury 1
HP:0002110 Bronchiectasis 1
HP:0002240 Hepatomegaly 1
HP:0002716 Lymphadenopathy 1
HP:0002835 Aspiration 1
HP:0003201 Rhabdomyolysis 1
HP:0004787 Fulminant hepatitis 1
HP:0005521 Disseminated intravascular coagulation 1
HP:0005523 Lymphoproliferative disorder 1
HP:0007185 Loss of consciousness 1
HP:0012223 Splenic rupture 1
HP:0012424 Chorioretinitis 1
HP:0012490 Panniculitis 1
HP:0100279 Ulcerative colitis 1
HP:0100584 Endocarditis 1
HP:0200120 Chronic active hepatitis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID