Harlequin syndrome

Harlequin syndrome (HSD) is an autonomic disorder occurring at any age and characterized by unilateral flushing and sweating, involving the face and sometimes arm and chest, in condition of thermal, exercise or emotional stress without sympathetic ocular manifestations. However, tonic pupils, parasympathetic oculomotor lesion and pre- or postganglionic sudomotor sympathetic deficit can rarely occur.



Input patient's signs and symptoms


Narrow down the case reports



Total: 48 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
1
(4.0%)
30066772
(6063119)
Do you know this syndrome? Harlequin syndrome.
Hans-Bittner NR, Bittner GC, Hans Filho G.
An Bras Dermatol. 2018;93(4):585-586.
Flushing
Adult Flushing Homo sapiens Hypohidrosis Male
1
(4.0%)
29652689
Postoperative Harlequin Syndrome: Case Report of a Rare but Clinically Striking Condition.
Kydes AT, Kelley AM, Pandya SR, Barst SM.
A A Pract. 2018;10(8):215-217.
Hyperhidrosis
1
(4.0%)
29411633
Harlequin syndrome following upper lobectomy.
Hussein N, Haqzad Y, Lodhia J, Begum S, Cowen M.
Asian Cardiovasc Thorac Ann. 2018;26(3):234-235.
Flushing
Females Flushing Homo sapiens Hypohidrosis Lung Neoplasms Middle Aged Nerve Block Pneumonectomy Thoracotomy
1
(4.0%)
29137067
(5690760)
Harlequin syndrome and Horner syndrome after neck schwannoma excision in a pediatric patient: A case report.
Lee DH, Seong JY, Yoon TM, Lee JK, Lim SC.
Medicine (Baltimore). 2017;96(45):e8548.
Horner syndrome
Child Flushing Head and Neck Neoplasms Homo sapiens Horner Syndrome Hypohidrosis Male Neck Dissection Neurilemmoma Postoperative Complications
1
(4.0%)
28878918
(5582228)
Development of Harlequin Syndrome following placement of thoracic epidural anesthesia in a pediatric patient undergoing Nuss procedure.
Lefevre A, Schnepper G.
Clin Case Rep. 2017;5(9):1523-1525.
Anhidrosis
1
(4.0%)
28689949
Three Extremely Rare Findings in the Same Patient: Harlequin Syndrome, Thyrocervical Trunk Aneurysm, and Systemic-Pulmonary Arterio-Arterial Fistula.
Goes Junior AMO, Koury Junior A, Paschoal EHA, Jeha SAH.
Ann Vasc Surg. 2017;45:267.e7-267.e12.
Neoplasm
Adult Aneurysm Computed Tomography Angiography Embolization, Therapeutic Females Flushing Homo sapiens Hypohidrosis Magnetic Resonance Angiography
1
(4.0%)
28382275
(5380209)
Harlequin Syndrome Following Resection of Mediastinal Ganglioneuroma.
Jeon YJ, Son J, Cho JH.
Korean J Thorac Cardiovasc Surg. 2017;50(2):130-132.
Flushing
1
(4.0%)
28316628
(5339527)
Idiopathic Harlequin Syndrome Manifesting during Exercise: A Case Report and Review of the Literature.
Algahtani H, Shirah B, Algahtani R, Alkahtani A.
Case Rep Med. 2017;2017:5342593.
Anhidrosis
1
(4.0%)
28291413
Harlequin sign concomitant with Horner syndrome after anterior cervical discectomy: a case of intrusion into the cervical sympathetic system.
Fringeli Y, Humm AM, Ansorge A, Maestretti G.
J Neurosurg Spine. 2017;26(6):684-687.
Ptosis
Cervical Vertebrae Diskectomy Females Flushing Homo sapiens Horner Syndrome Hypohidrosis Intervertebral Disk Displacement Middle Aged Postoperative Complications Radiculopathy
1
(4.0%)
27024906
A Case of Undiagnosed Harlequin Syndrome Presenting in General Dental Practice.
Edwards K, Schaefer A, Greenwood M, Staines K.
Dent Update. 2016;43(1):90-2.
Flushing
Bruxism Dentist Differential Diagnosis Females Flushing Homo sapiens Hypohidrosis Middle Aged Neurologic Examination Temporomandibular Joint Dysfunction Syndrome
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 11

HPO ID Term # of case reports
HP:0031284 Flushing 23
HP:0002277 Horner syndrome 4
HP:0000970 Anhidrosis 3
HP:0000975 Hyperhidrosis 3
HP:0000616 Miosis 2
HP:0010783 Erythema 2
HP:0000508 Ptosis 1
HP:0000853 Goiter 1
HP:0002076 Migraine 1
HP:0012074 Tonic pupil 1
HP:0100008 Schwannoma 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID